Answers are grounded in this paper and cite their sources.
Styrylquinoline derivatives are demonstrated to be HIV-1 integrase inhibitors. On the basis of our previous CoMFA analysis of a series of styrylquinoline derivatives, N-[(2-substituted-styryl)-5-chloro-8-hydroxyquinolin-7-yl]-benzenesulfonamide derivatives were designed and synthesized,and their possible HIV IN inhibitory activity was evaluated.
No takes yet. Share an insight, caveat, or question.
Jiao et al. (2010) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: