Key result
Single defibrillator testing during ICD implantation showed no significant differences in neuronal damage or cognitive impairment compared to untested patients.
Why the study?
Studies have shown increases in neuronal damage markers after defibrillator threshold testing with multiple shocks, prompting evaluation of the effects of a single DFT.
Does single defibrillator testing (DFT) cause neuronal damage or cognitive impairment in patients undergoing transvenous ICD implantation?
Population
23 patients undergoing transvenous ICD implantation
Follow-up
24 h postsurgery
Authors
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Single DFT was not associated with added neuronal or cognitive risk; leaves open whether routine testing can be safely omitted.
Observational (n=23)
Does single defibrillator testing (DFT) cause neuronal damage or cognitive impairment in patients undergoing transvenous ICD implantation?
Single defibrillator testing during ICD implantation does not lead to signs of neuronal damage or cognitive impairment in selected patients without pre-existing cerebral vasculopathy.
Gestrich et al. (2021) conducted an observational in Transvenous ICD implantation (n=23). Single defibrillator testing (DFT) vs. No defibrillator testing was evaluated on Clinical outcomes, neuronal damage parameters (NSE and S100), and intraoperative cerebral perfusion. Single defibrillator testing during ICD implantation showed no significant differences in neuronal damage or cognitive impairment compared to untested patients.
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