Key result
Higher carotid artery stiffness was independently associated with slower processing speed (B = -0.60, P=0.002) but not working memory in healthy middle-aged/older adults.
Population
51 healthy adults with low cardiovascular disease risk factor burden, comprising 32 middle-aged/older adults…
Design
Cross-sectional
Authors
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Supports vascular contributions to cognitive slowing in aging; leaves open causality and need for interventional trials.
Cross-Sectional (n=51)
Effect estimate: B = -0.60
p-value: p=0.002
Age-related increases in carotid artery stiffness are independently associated with slower processing speed in healthy middle-aged and older adults, suggesting vascular stiffening may contribute to early cognitive decline.
DuBose et al. (2017) conducted a cross-sectional in Healthy aging (n=51). Carotid artery stiffness vs. Lower carotid artery stiffness was evaluated on Processing speed (B = -0.60, p=0.002). Higher carotid artery stiffness was independently associated with slower processing speed (B = -0.60, P=0.002) but not working memory in healthy middle-aged/older adults.
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