Key result
Gelsolin is a multifunctional actin-binding protein whose dysregulation is implicated in various diseases including cancer, Alzheimer's disease, and rheumatoid arthritis.
Design
Review
Authors
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Supports gelsolin as a cross-disease target for investigation; leaves open clinical validation in prospective trials.
This review summarizes the structure, regulation, and functional roles of gelsolin, highlighting its potential as a therapeutic target in various diseases.
Feldt et al. (2018) conducted a review in Gelsolin-related diseases (Alzheimer's disease, rheumatoid arthritis, cancer). Gelsolin was evaluated. Gelsolin is a multifunctional actin-binding protein whose dysregulation is implicated in various diseases including cancer, Alzheimer's disease, and rheumatoid arthritis.
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