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Alginate, chitosan and gelatin were deposited on the surface of PDL-LA films via an entrapment method. ATR-FT-IR, XPS and contact-angle analyses revealed the formation of stable thin biomacromolecule layers on the PDL-LA film, thus enhancing the hydrophilicity of the films. Confocal laser scanning microscopy showed the existence of entrapment areas of approximately 10–20 μm in depth. This simple surface-treatment method may have the potential for many biomedical applications.
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Zhu et al. (2002) studied this question.
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