Key result
Hypertrophic cardiomyopathy was associated with significantly increased left atrial volume and sphericity index, and decreased left atrial phasic functions compared to healthy controls (p<.001).
Why the study?
Left atrial remodelling in hypertrophic cardiomyopathy is not fully understood, and a comprehensive evaluation of left atrial alterations using cardiac magnetic resonance imaging was lacking.
Does cardiac magnetic resonance imaging reveal differences in left atrial geometry and function between patients with hypertrophic cardiomyopathy and healthy controls?
Case-Control (n=210)
Does cardiac magnetic resonance imaging reveal differences in left atrial geometry and function between patients with hypertrophic cardiomyopathy and healthy controls?
p-value: p=<.001
Cardiac MRI demonstrates that left atrial phasic functions are impaired and directly related to left atrial enlargement in patients with hypertrophic cardiomyopathy.
No takes yet. Share an insight, caveat, or question.
LA changes in HCM are hypothesis-generating; prospective studies needed before informing risk stratification or practice.
Mureşan et al. (2022) conducted a case-control in Hypertrophic cardiomyopathy (n=210). Hypertrophic cardiomyopathy vs. Healthy controls was evaluated on Left atrial volume (LAV), sphericity index (LASI), and phasic functions (p=<.001). Hypertrophic cardiomyopathy was associated with significantly increased left atrial volume and sphericity index, and decreased left atrial phasic functions compared to healthy controls (p<.001).
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