Key result
Baseline stroke volume variation significantly correlated with changes in cardiac index in response to fluid loading (r = 0.64, P = 0.02) in patients with severe sepsis.
Why the study?
Does stroke volume variation predict changes in cardiac index in response to fluid loading in mechanically ventilated patients with severe sepsis?
Population
10 mechanically ventilated patients with severe sepsis or septic shock in a university hospital
Comparison
Fluid loading with 500 mL 10% hydroxyethylstarch… vs Baseline (before fluid loading)
Design
Cohort
Follow-up
30 min
Authors
Loading...
SVV may predict fluid responsiveness in severe sepsis; leaves open need for randomized validation before practice change.
Does stroke volume variation predict changes in cardiac index in response to fluid loading in mechanically ventilated patients with severe sepsis?
Effect estimate: r = 0.64
p-value: p=0.02
Stroke volume variation is a useful hemodynamic parameter for predicting fluid responsiveness in mechanically ventilated patients with severe sepsis.
Marx et al. (2004) studied severe sepsis or septic shock (n=10). Fluid loading with 10% hydroxyethylstarch 200/0.5 was evaluated on Correlation between baseline stroke volume variation and changes in cardiac index in response to fluid loading (r = 0.64, p=0.02). Baseline stroke volume variation significantly correlated with changes in cardiac index in response to fluid loading (r = 0.64, P = 0.02) in patients with severe sepsis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: