Key result
Magnetic resonance imaging metrics hold significant promise as potential surrogate endpoints for the accumulation of physical disability in multiple sclerosis clinical trials.
This review highlights the potential of conventional and non-conventional MRI metrics as surrogate endpoints for physical disability accumulation in multiple sclerosis clinical trials.
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May accelerate MS trial design via MRI surrogates; leaves open prospective validation before adoption.
Bar-Zohar et al. (2008) conducted a review in Multiple sclerosis. Magnetic resonance imaging metrics was evaluated. Magnetic resonance imaging metrics hold significant promise as potential surrogate endpoints for the accumulation of physical disability in multiple sclerosis clinical trials.
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