Key result
Patients aged 80 and older undergoing colorectal cancer surgery had comparable length of stay (P=0.21) and rates of complications including mortality (P=0.67) compared to those younger than 80.
Why the study?
Despite the prevalence of colorectal cancer in the elderly, recent studies examining post-operative outcomes in these patients have been lacking.
Does age 80 and above worsen post-operative outcomes in adults receiving surgical resections for colorectal cancer?
Cohort (n=326)
No
Does age 80 and above worsen post-operative outcomes in adults receiving surgical resections for colorectal cancer?
p-value: p=0.21 for length of stay; 0.67 for complications
Elderly patients aged 80 and above can achieve comparable post-operative outcomes to younger patients following colorectal cancer surgery with appropriate selection.
Supports considering surgery in selected octogenarians; leaves open need for prospective validation before changing practice.
BACKGROUND: Despite the prevalence of colorectal cancer in the elderly, there has been a lack of recent studies examining surgical outcomes in these patients. Post-operative outcomes of colorectal cancer surgeries in those aged 80 and above will be compared to those younger than 80. METHODS: A retrospective study was conducted of adults receiving surgical resections at a single tertiary centre for colorectal cancer diagnosed between January 2017 and December 2019. Patient demographics, mode of presentation, tumour demographics, operative data and post-operative outcomes were investigated. RESULTS: Of the 326 patients included, 56 were aged 80 and above. Older patients were more likely to be female (P = 0.02), present with surgical emergencies or from other workup rather than through screening (P = 0.002), have more locally advanced cancers (P = 0.009) and receive less neoadjuvant therapy (P = 0.016). Despite this, they had comparable outcomes to those younger than 80 in terms of length of stay (P = 0.21) and rates of complications including mortality (P = 0.67). CONCLUSION: With appropriate patient selection and management, elderly patients can achieve comparable post-operative outcomes to their younger counterparts.
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Park et al. (2020) conducted a cohort in Colorectal cancer (n=326). Age ≥80 years vs. Age <80 years was evaluated on Length of stay and rates of complications including mortality (p=0.21 for length of stay; 0.67 for complications). Patients aged 80 and older undergoing colorectal cancer surgery had comparable length of stay (P=0.21) and rates of complications including mortality (P=0.67) compared to those younger than 80.
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