Key result
Carotid endarterectomy linked to an absolute ~33% reduction in recurrent stroke vs medical therapy.
Cohort (n=34)
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Between 1978 and 1988, the diagnosis of atheromatous pseudo-occlusion of the internal carotid artery was made in 34 patients by angiography. Results of noninvasive tests were abnormal in 33 of the 34 patients examined. Twenty-five patients had carotid endarterectomy, and the other nine were treated medically. Four of the 34 patients (12%) had significant complications, two related to angiography and two to surgery. Twenty-three of the 25 operated patients were seen in long-term follow-up; 19 (83%) were found to have a patent operated vessel by noninvasive testing. None of the 23 operated patients followed up suffered recurrent neurologic deficits following surgery; two had distant contralateral strokes. Three of the nine patients treated medically (33%) experienced delayed ipsilateral stroke. This study shows that the risks associated with angiography and surgery for atheromatous pseudo-occlusion are significant and are higher than previously reported.
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O'Leary et al. (1989) conducted a cohort in Atheromatous pseudo-occlusion of the internal carotid artery (n=34). Carotid endarterectomy vs. Medical treatment was evaluated on Recurrent neurologic deficits or delayed ipsilateral stroke. Carotid endarterectomy was associated with 0% recurrent neurologic deficits in long-term follow-up, compared to a 33% rate of delayed ipsilateral stroke in medically treated patients.
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