Key result
Multiphase post-mortem CT angiography successfully detected a right coronary artery filling defect indicative of coronary thrombosis, which was confirmed by autopsy and histology.
Why the study?
Literature in Italy on post-mortem angiography lacks a solid foundation, especially in criminal court proceedings, and demonstration of concordance between MPMCTA and standard autopsy in acute coronary thrombosis was needed.
Does multiphase post-mortem CT angiography (MPMCTA) accurately detect coronary thrombosis compared to autopsy and histology in a post-mortem setting?
Case Report (n=1)
Does multiphase post-mortem CT angiography (MPMCTA) accurately detect coronary thrombosis compared to autopsy and histology in a post-mortem setting?
Multiphase post-mortem CT angiography can accurately detect acute coronary thrombosis, showing concordance with traditional autopsy and histology.
Single-case success supports multiphase post-mortem CT angiography feasibility for coronary thrombosis; leaves open validation before forensic adoption.
While post-mortem angiography (PMA) is gradually establishing its role in Forensic Radiology, the available literature in Italy lacks a solid foundation, particularly regarding its use in criminal court proceedings. An illustrative example of multiphase post-mortem CT angiography (MPMCTA) is presented here to encourage the systematic implementation of PMA methods. To demonstrate concordance between MPMCTA and the reference standard (autopsy and histology) in a case of acute coronary thrombosis, we report a case where MPMCTA, autopsy, histological and toxicological analyses were performed on a previously healthy 51-year-old man. MPMCTA detected a right coronary artery filling defect that could be ascribed to coronary thrombosis, which was later confirmed by autopsy and histological examinations.
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Jessika et al. (2021) conducted a case report in Acute coronary thrombosis (n=1). Multiphase post-mortem CT angiography (MPMCTA) vs. Autopsy and histology was evaluated on Detection of coronary thrombosis. Multiphase post-mortem CT angiography successfully detected a right coronary artery filling defect indicative of coronary thrombosis, which was confirmed by autopsy and histology.
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