June 7, 2005Journal of Hypertension
Simultaneous echocardiography and myocardial perfusion single photon emission computed tomography associated with dobutamine stress to predict long-term cardiac mortality in normotensive and hypertensive patients
Key result
Dobutamine stress echocardiography and SPECT were equally effective in predicting long-term cardiac death in normotensive and hypertensive patients, with higher survival for negative results (P<0.001).
Why the study?
Are simultaneous dobutamine stress echocardiography and SPECT equally effective in predicting long-term cardiac mortality in normotensive and hypertensive patients?
Population
301 consecutive patients undergoing dobutamine stress testing for assessing risk in coronary artery disease…
Comparison
Simultaneous dobutamine stress echocardiography… vs Comparison between echocardiography and SPECT…
Design
Cohort
Follow-up
7.3 +/- 2.8 years
Authors
Discussion
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Member takes
Implication
May support interchangeable use of either test for mortality risk stratification; extends comparisons to hypertensive patients but leaves open management impact.
Study Design
Type
Cohort (n=301)
Structured PICO
Are simultaneous dobutamine stress echocardiography and SPECT equally effective in predicting long-term cardiac mortality in normotensive and hypertensive patients?
P
Population
301 normotensive and hypertensive patients undergoing dobutamine stress with simultaneous echocardiography and SPECT, followed for a mean of 7.3 years.
E
Exposure
Simultaneous dobutamine stress echocardiography and Tc-sestamibi single photon emission computed tomography (SPECT)
C
Comparator
Comparison between echocardiography and SPECT, and between normotensive and hypertensive patients
O
Outcome
Long-term cardiac mortalityhard clinical
Main Result
p-value: p=<0.001
Dobutamine stress echocardiography and SPECT are equally effective in predicting long-term cardiac death in both normotensive and hypertensive patients.
Cite This Study
Bigi et al. (2005) conducted a cohort in Coronary artery disease (n=301). Dobutamine stress echocardiography and SPECT vs. Normal test results was evaluated on Long-term cardiac mortality (p=<0.001). Dobutamine stress echocardiography and SPECT were equally effective in predicting long-term cardiac death in normotensive and hypertensive patients, with higher survival for negative results (P<0.001).