Key result
Electro-acupuncture reduces post-stroke cerebral oedema in rats, increasing relative apparent diffusion coefficient.
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PRIMARY OBJECTIVE: This study was designed to determine whether electro-acupuncture (EA) could alleviate cerebral oedema after cerebral ischemia. RESEARCH DESIGN: EA has been widely used for cerebrovascular disease in East Asian countries. However, whether EA might reduce cerebral oedema after stroke remains unclear. In the current study, diffusion-weighted MRI, which is a reliable method for detecting cerebral oedema, was used to determine whether EA could ameliorate cerebral oedema. METHODS AND PROCEDURES: Twelve rats with induced strokes were divided into two groups: one group with EA treatment (EA group) and one group without EA treatment (non-EA group). Both groups of rats underwent MRI scanning at the same time point following ischemia. MAIN OUTCOMES AND RESULTS: Diffusion-weighted imaging showed that the relative apparent diffusion coefficient increased significantly in the cortical and sub-cortical areas of the EA group relative to the non-EA group, indicating that EA can alleviate cerebral oedema after ischemic stroke. CONCLUSIONS: Electro-acupuncture can alleviate cerebral oedema in rats following ischemia.
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Zhang et al. (2011) studied Cerebral ischemia / ischemic stroke (n=12). Electro-acupuncture (EA) vs. No electro-acupuncture treatment was evaluated on Relative apparent diffusion coefficient (cerebral oedema) on diffusion-weighted MRI. Electro-acupuncture significantly increased the relative apparent diffusion coefficient in cortical and sub-cortical areas of rats, indicating alleviation of cerebral oedema after ischemic stroke.
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