Key result
Only 55.1% of high-risk atrial fibrillation patients were on oral anticoagulation before a stroke or TIA, commonly withheld due to infrequent AF, previous bleeds, or patient preference.
Why the study?
What are the reasons for underuse of oral anticoagulation in high-risk patients with atrial fibrillation who suffer a stroke or TIA?
Population
3404 patients with previously diagnosed atrial fibrillation who suffered a total of 2955 ischaemic strokes…
Comparison
Oral anticoagulation (OAC) vs No oral anticoagulation
Design
Cohort
Authors
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OAC underuse persists before stroke in high-risk AF; leaves open effective strategies to address common withholding reasons.
Observational (n=3,404)
What are the reasons for underuse of oral anticoagulation in high-risk patients with atrial fibrillation who suffer a stroke or TIA?
Underuse of oral anticoagulation is a common contributor to ischemic strokes and TIAs in patients with atrial fibrillation, often due to infrequent AF episodes, previous bleeds, and patient preference.
Palomäki et al. (2015) conducted an observational in Atrial fibrillation with stroke or TIA (n=3,404). Oral anticoagulation (OAC) vs. No OAC was evaluated on Proportion of high-risk patients (CHADS2 ≥2) on OAC before the onset of stroke or TIA. Only 55.1% of high-risk atrial fibrillation patients were on oral anticoagulation before a stroke or TIA, commonly withheld due to infrequent AF, previous bleeds, or patient preference.
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