Key result
Community-based cardiac rehabilitation was associated with a significant reduction in low-density lipoprotein levels compared to regular care (-0.3 vs. +0.2 mmol/L) over one year in patients with cardiovascular disease.
Why the study?
Does a community-based cardiac rehabilitation program improve low density lipoprotein levels and other clinical parameters in patients with cardiovascular disease?
Cohort (n=251)
Yes
Does a community-based cardiac rehabilitation program improve low density lipoprotein levels and other clinical parameters in patients with cardiovascular disease?
Absolute Event Rate: -0.3% vs 0.2%
p-value: p=<0.01
A community-based cardiac rehabilitation program significantly improves lipid profiles, fasting blood glucose, and blood pressure in patients with cardiovascular disease compared to standard care.
Hypothesis-generating for community cardiac rehab in CVD; requires RCTs before practice change.
BACKGROUND: Cardiac rehabilitation (CR) programmes have been shown to improve patient outcomes, but vary widely in their components. The impact of Singapore's CR programme on clinical outcomes is currently not known. OBJECTIVE: To evaluate the effects of a community-based CR programme on important clinical parameters in patients with cardiovascular disease in Singapore. METHOD: A retrospective cohort study was conducted. Cardiovascular patients who had completed a hospital-based CR programme were included. Patients who continued with community-based CR (n = 94) during the period of 2009-2013 were compared with patients who received regular care (n = 157). Changes in clinical and physical examination parameters between baseline and one-year post follow-up were analyzed. Within-group differences were compared using the paired t-test, while multivariate linear regression was used to compare the changes in the various parameters between the intervention and control groups. The primary outcome measure was low density lipoprotein (LDL) levels. RESULTS: Patients in the intervention group had significant lowering of LDL (2.5 to 2.2 mmol/L, p<0.01), while the control group's LDL increased (2.2 to 2.4 mmol/L, p<0.01). The intervention group had greater improvements in LDL (-0.3 vs. +0.2 mmol/L, p<0.01), triglycerides (-0.1 vs. +0.1 mmol/L, p=0.01), total cholesterol (-0.3 vs. +0.3 mmol/L, p<0.01), fasting blood glucose (-0.5 vs. +0.3 mmol/L, p<0.01), systolic blood pressure (-3.2 vs. +5 mmHg, p<0.01) and diastolic blood pressure (-2.6 vs. +2.8 mmHg, p<0.01). CONCLUSION: The community-based CR programme in Singapore is associated with improvements in several cardiovascular clinical parameters and may be of benefit to cardiovascular patients.
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Ong et al. (2016) conducted a cohort in Cardiovascular disease (n=251). Community-based cardiac rehabilitation vs. Regular care was evaluated on Change in low density lipoprotein (LDL) levels (p=<0.01). Community-based cardiac rehabilitation was associated with a significant reduction in low-density lipoprotein levels compared to regular care (-0.3 vs. +0.2 mmol/L) over one year in patients with cardiovascular disease.
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