The Skin and Bladder of Amphibians as Models for the Mammalian Nephron

Properties of the skin and bladder of amphibians have been reviewed and compared with those of the nephrons of mammals. Though the skin and the bladder have proved to be useful models for the understanding of problems of permeability of the most distal parts of the nephron, they must be treated with caution, since from evidence derived from micropuncture techniques there are some important differences, which are discussed.