What question did this study set out to answer?

To identify which magnetic resonance imaging parameters are most sensitive and convenient for tracking in vivo temperature changes during radio frequency hyperthermia.

May 1, 1990Journal of Computer Assisted Tomography

Observation by MR Imaging of In Vivo Temperature Changes Induced by Radio Frequency Hyperthermia

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Authors

AHAlistair S. HallBroad Institute MPMichael V. PriorHammersmith Hospital JHJ. W. HandSt Thomas' Hospital

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Implication

Experimental study demonstrates MR tracking of tissue heating via T1 and diffusion shifts in human volunteers, highlighting feasible parameters for noninvasive thermal therapy monitoring.

Key Points

To identify which magnetic resonance imaging parameters are most sensitive and convenient for tracking in vivo temperature changes during radio frequency hyperthermia.
Applied radio frequency hyperthermia to human volunteers inside an MRI system across a temperature span of approximately 28 °C to 42 °C.
Acquired sequential MR imaging measurements to evaluate changes in T1, T2, tissue perfusion, and water diffusion.
T1 values exhibited a temperature-dependent increase of approximately 1.3%/°C, matching theoretical predictions.
The diffusion coefficient increased by approximately 2.4%/°C across the 28 °C to 42 °C range, showing strong agreement with theoretical models.

Cite This Study

Hall et al. (1990) studied this question.

synapsesocial.com/papers/6a7073ea6ceb2bbd16dfe556 https://doi.org/10.1097/00004728-199005000-00021

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Implication

Experimental study demonstrates MR tracking of tissue heating via T1 and diffusion shifts in human volunteers, highlighting feasible parameters for noninvasive thermal therapy monitoring.

Observation by MR Imaging of In Vivo Temperature Changes Induced by Radio Frequency Hyperthermia

Discussion

Member takes

Implication

Key Points

Cite This Study

Observation by MR Imaging of In Vivo Temperature Changes Induced by Radio Frequency Hyperthermia

Discussion

Member takes

Implication

Key Points

Cite This Study

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