July 1, 1997HeartOpen Access

Can abnormalities of ventricular repolarisation identify insulin dependent diabetic patients at risk of sudden cardiac death?

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Population

31 young asymptomatic, normotensive, insulin dependent diabetic patients, aged 20-55 years with normal…

Design

Cross-sectional, Single observer blinded to other data about the patients

Authors

PWP.J. WestonRoyal Liverpool and Broadgreen University Hospital NHS Trust JGJames GlancyCounty Hospital PMPaul G. McNallyRoyal College of Surgeons in Ireland

Discussion

Member takes

Implication

Hypothesis-generating for BRS-QTc link in diabetes; prospective studies needed before clinical or mechanistic inferences.

Structured PICO

Population

31 young asymptomatic, normotensive, insulin dependent diabetic patients, aged 20-55 years with normal clinical autonomic function.

Intervention

Measurement of QT dispersion and mean QTc intervals from standard 12 lead electrocardiograms

Outcome

Association of QT dispersion and mean QTc intervals with baroreceptor-cardiac reflex sensitivity (BRS)surrogate

In insulin-dependent diabetic patients, abnormal baroreflex sensitivity correlates with global prolongation of ventricular repolarization (QTc) rather than QT dispersion, which may partly explain their increased risk of sudden cardiac death.

Cite This Study

Weston et al. (1997) studied this question.

synapsesocial.com/papers/6a70744126a7f98052dcf4c7 https://doi.org/10.1136/hrt.78.1.56

View Full Paper

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Can abnormalities of ventricular repolarisation identify insulin dependent diabetic patients at risk of sudden cardiac death?

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Can abnormalities of ventricular repolarisation identify insulin dependent diabetic patients at risk of sudden cardiac death?

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider