Key result
Modernized preoperative management and surgical techniques for innominate artery lesions eliminated in-hospital thrombosis, mediastinitis, myocardial infarction, and mortality compared to older methods.
Why the study?
The immediate surgical outcomes of intrathoracic reconstructions for atherosclerotic lesions of the innominate artery across different eras of management and surgical technique required evaluation.
Does a modernized surgical approach and preoperative management improve in-hospital outcomes in patients undergoing intrathoracic innominate artery reconstructions compared to historical techniques?
Cohort (n=79)
Does a modernized surgical approach and preoperative management improve in-hospital outcomes in patients undergoing intrathoracic innominate artery reconstructions compared to historical techniques?
Modernizing preoperative management (including coronary angiography) and surgical technique (partial sternotomy, multiple replacement) for innominate artery lesions eliminated thrombotic, purulent, and cardiac complications and reduced neurological complications and mortality.
Retrospective series on innominate reconstructions leave optimal technique open; prospective trials required before practice change.
Objective. To evaluate the immediate results of surgical treatment of atherosclerotic lesions of innominate artery. Material and methods. During the period between 1983 and 2022, 180 interventions were performed for atherosclerotic lesions of innominate artery including 79 intrathoracic reconstructions. Patients were divided into 2 groups due to some changes in preoperative management and surgical technique. In the first group (n=47, 1983—1999), coronary angiography was not performed. Surgical access was performed through median sternotomy. Endarterectomy with linear replacement was performed for lesion of innominate artery bifurcation. In the second group (n=32, 2000—2020), coronary angiography with stenting was performed if necessary. Surgical access was performed through partial sternotomy, and multiple replacement of supra-aortic vessels was carried out for lesion of innominate artery bifurcation. Results. In-hospital complications: thrombosis — 3 (3.8%), stroke (right hemisphere) — 3 (3.8%), bleeding with re-sternotomy — 4 (5.1%), mediastinitis — 6 (7.6%), myocardial infarction — 4 (5.1%) cases. Mortality rate was 3.8% (n=3). Thrombosis, mediastinitis, myocardial infarction and mortality were not observed in the second group. Incidence of stroke was 1.4 times lower than in the first group. Two cases of thrombosed prosthesis in the first group arose after endarterectomy from innominate artery bifurcation with linear replacement. Stroke (p=0.003) and mediastinitis (p=0.000) were more common in patients with postoperative thrombosis of vascular prosthesis. Conclusion. Changing the principles of preoperative management, choice of traumatic approach and changing surgical technique for atherosclerotic lesions of innominate artery made it possible to exclude thrombotic, purulent and cardiac complications, reduce the incidence of neurological complications and mortality.
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Beloyartsev et al. (2023) conducted a cohort in Atherosclerotic lesions of innominate artery (n=79). Modernized surgical technique (partial sternotomy, multiple replacement) and preoperative management vs. Older surgical technique (median sternotomy, endarterectomy) and management was evaluated on In-hospital complications and mortality. Modernized preoperative management and surgical techniques for innominate artery lesions eliminated in-hospital thrombosis, mediastinitis, myocardial infarction, and mortality compared to older methods.
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