What question did this study set out to answer?

To evaluate the four-decade trajectory of mortality from nontuberculous mycobacteriosis, analyze regional variations, and estimate disease prevalence in Japan.

January 1, 2014Annals of the American Thoracic Society

A Steady Increase in Nontuberculous Mycobacteriosis Mortality and Estimated Prevalence in Japan

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Authors

KMKozo MorimotoUniversity of Nagasaki KIKazuro IwaiJapan Anti Tuberculosis Association KUKazuhiro UchimuraJapan Anti Tuberculosis Association

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Implication

Epidemiological study reveals rising mortality and estimated prevalence of pulmonary nontuberculous mycobacteriosis in Japan, highlighting an expanding public health burden.

Key Points

To evaluate the four-decade trajectory of mortality from nontuberculous mycobacteriosis, analyze regional variations, and estimate disease prevalence in Japan.
Extracted mortality and regional distribution data for nontuberculous mycobacteriosis from Japanese Vital Statistics and census records to calculate crude, age-adjusted, and standardized mortality ratios from 1970 to 2010.
Tracked 309 registered patients with pulmonary nontuberculous mycobacteriosis in a 5-year follow-up cohort from 2004 to 2006 to establish prognosis and annual mortality rates.
Crude mortality rates increased steadily for both sexes after 1970, with female mortality surpassing male rates after 2005 and age-adjusted rates rising gradually in women through 2010.
Standardized mortality ratios were significantly elevated in central and western Japan, with the highest concentrations occurring along southern Pacific coastal regions.
The clinical cohort demonstrated an annual mortality rate of 1% to 2%, yielding an estimated disease prevalence 6- to 10-fold higher than annual incidence.

Cite This Study

Morimoto et al. (2014) studied this question.

synapsesocial.com/papers/6a7077958031ec7bb1dc5d12 https://doi.org/10.1513/annalsats.201303-067oc

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Implication

Epidemiological study reveals rising mortality and estimated prevalence of pulmonary nontuberculous mycobacteriosis in Japan, highlighting an expanding public health burden.

A Steady Increase in Nontuberculous Mycobacteriosis Mortality and Estimated Prevalence in Japan

Discussion

Member takes

Implication

Key Points

Cite This Study

A Steady Increase in Nontuberculous Mycobacteriosis Mortality and Estimated Prevalence in Japan

Discussion

Member takes

Implication

Key Points

Cite This Study

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