Key result
Streptokinase treatment for cardiac prosthetic thrombosis achieved a 64.8% success rate, with all double-disk prostheses responding, though a fatal hemorrhagic complication occurred in 5.8%.
Why the study?
Does streptokinase infusion improve thrombus resolution in patients with cardiac prosthetic thrombosis?
Population
17 patients with cardiac prosthetic thrombosis diagnosed by clinical, echocardiographic, and radioscopic…
Design
Case_series
Follow-up
mean 42 months
Authors
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May support streptokinase in select double-disk cases; leaves open safety and efficacy pending controlled trials.
Observational (n=17)
Does streptokinase infusion improve thrombus resolution in patients with cardiac prosthetic thrombosis?
Streptokinase is an effective treatment for thrombosis in double-disk cardiac prostheses, though it carries significant bleeding and embolic risks.
Ramos et al. (2003) conducted an observational in Cardiac prosthetic thrombosis (n=17). Streptokinase was evaluated on Success rate (resolution of thrombosis). Streptokinase treatment for cardiac prosthetic thrombosis achieved a 64.8% success rate, with all double-disk prostheses responding, though a fatal hemorrhagic complication occurred in 5.8%.
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