Key result
ICD-10 substance use codes demonstrated high specificity and positive predictive value but low sensitivity, with the opioid code (F11) yielding a sensitivity of 42.6% (95% CI 36.3-49.1).
Why the study?
Healthcare databases offer epidemiological research potential in people who inject drugs, but the validity of ICD-10 codes for specific substances in this population has not been assessed.
Are ICD-10 substance use codes valid for identifying specific substance use in patients with infective endocarditis?
Population
379 first-episode infective endocarditis patients aged 18–55 across three hospitals
Comparison
ICD-10 substance use codes vs self-reported substance use on medical record review
Design
Cohort validation study
Authors
Loading...
ICD-10 substance codes show high specificity but low sensitivity in endocarditis; leaves open need for supplementary methods in research and surveillance.
Cohort (n=379)
Yes
Are ICD-10 substance use codes valid for identifying specific substance use in patients with infective endocarditis?
ICD-10 substance use codes in endocarditis patients have high specificity and PPV but low sensitivity, requiring adjustment for low sensitivity if used in research.
Campanile et al. (2022) conducted a cohort in First-episode infective endocarditis (n=379). ICD-10 substance use codes vs. Self-reported substance use (medical record review) was evaluated on Sensitivity, specificity, PPV, and NPV of ICD-10 substance use codes. ICD-10 substance use codes demonstrated high specificity and positive predictive value but low sensitivity, with the opioid code (F11) yielding a sensitivity of 42.6% (95% CI 36.3-49.1).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: