Why the study?
Does thrombolytic therapy improve outcomes in patients with suspected myocardial infarction presenting with ST segment depression compared to those with ST segment elevation?
Does thrombolytic therapy improve outcomes in patients with suspected myocardial infarction presenting with ST segment depression compared to those with ST segment elevation?
Patients with suspected MI and ST segment depression face high mortality that is poorly responsive to thrombolytic therapy, despite having less myocardial damage than those with ST elevation.
ST depression in suspected MI signals high mortality poorly responsive to thrombolysis; leaves open whether alternative strategies benefit this subgroup.
Patients with suspected myocardial infarction presenting with ST segment depression Acute myocardial infarction in association with predominant ST segment depression on the electrocardiogram is accompanied by high mortality that appears to be little influenced by thrombolytic therapy.'-3 Patients with ST segment depression have less myocardial damage but a poorer outcome than those with initial ST segment elevation.3
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Lee et al. (1997) studied this question.
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