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January 1, 1996Annals of Noninvasive Electrocardiology

Adverse Prognosis of ST Depression on the Resting Electrocardiogram in Stable Patients Following Acute Myocardial Infarction

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Why the study?

Does resting ST segment depression predict cardiac death and hospitalization for acute myocardial infarction or unstable angina in stable patients following an acute ischemic event?

Population

936 stable patients following an acute ischemic event, comprising 99 patients with ST depression and 837…

Comparison

Presence of ST segment depression on resting ECG vs Absence of ST segment depression on resting ECG

Design

Cohort

Authors

EDEdward M. DwyerRutgers, The State University of New Jersey
Robert B. Case
Robert B. CaseElectrophysiology
JGJohn A. GillespieRutgers, The State University of New Jersey

Discussion

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Implication

ST depression may stratify post-MI risk; leaves open incremental value beyond clinical scores in modern cohorts.

Structured PICO

Does resting ST segment depression predict cardiac death and hospitalization for acute myocardial infarction or unstable angina in stable patients following an acute ischemic event?

P
Population
936 stable patients following an acute ischemic event (infarction or unstable angina), comprising 99 patients with ST depression and 837 patients without ST depression on the resting ECG.
I
Intervention
Presence of ST segment depression on resting ECG
C
Comparator
Absence of ST segment depression on resting ECG
O
Outcome
Cardiac death and hospitalization for acute myocardial infarction or unstable anginahard clinical

Resting ST segment depression on ECG is a marker of adverse prognosis (cardiac death and reinfarction) specifically in patients recovering from acute myocardial infarction, likely reflecting older age and more severe underlying coronary disease.

Cite This Study

Dwyer et al. (1996) studied this question.

synapsesocial.com/papers/6a707ea975498292b709edc7https://doi.org/10.1111/j.1542-474x.1996.tb00262.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Prognostic Importance of the Electrocardiogram After Myocardial Infarction1972 · 143 citations
  2. 2Clinical and prognostic importance of persistent precordial (V1-V4) electrocardiographic ST segment depression in patients with inferior transmural myocardial infarction.1986 · 53 citations
  3. 3Significance of initial ST segment elevation and depression for the management of thrombolytic therapy in acute myocardial infarction. European Cooperative Study Group for Recombinant Tissue-Type Plasminogen Activator.1990 · 165 citations
  4. 4Clinical classification of cardiac deaths.1982 · 640 citations
  5. 5Very early risk stratification by electrocardiogram at rest in men with suspected unstable coronary heart disease1993 · 150 citations