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November 18, 2008Cardiology

Angina pectoris and ST-Segment Depression during Exercise Testing Early following Acute Myocardial Infarction

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Why the study?

Does the presence of ST-segment depression or angina pectoris during exercise testing 3 weeks after acute myocardial infarction predict acute coronary events?

Population

281 consecutive survivors of acute myocardial infarction who underwent exercise testing 3 weeks after the…

Comparison

Presence of ST-segment depression and/or angina… vs Absence of ST-segment depression and angina…

Design

Cohort

Follow-up

1 year

Authors

LAL. AbboudTechnion – Israel Institute of TechnologyJHJamal HirTechnion – Israel Institute of TechnologyIEIris EisenRambam Health Care Campus

Discussion

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Implication

Early post-MI exercise ischemia markers do not predict events; leaves open their role in contemporary risk models.

Structured PICO

Does the presence of ST-segment depression or angina pectoris during exercise testing 3 weeks after acute myocardial infarction predict acute coronary events?

P
Population
281 consecutive survivors of acute myocardial infarction who underwent exercise testing 3 weeks after the event (out of 570 total survivors)
I
Intervention
Presence of ST-segment depression (≥1 mm) and/or angina pectoris during exercise testing
C
Comparator
Absence of ST-segment depression and angina pectoris during exercise testing
O
Outcome
Composite of acute coronary events (cardiac death, myocardial infarction, unstable angina pectoris requiring hospitalization) during the subsequent yearcomposite

Clinical or ECG evidence of myocardial ischemia during exercise testing 3 weeks after acute myocardial infarction does not predict acute coronary events at 1 year.

Cite This Study

Abboud et al. (2008) studied this question.

synapsesocial.com/papers/6a8bf241de5ec4e001e3de3dhttps://doi.org/10.1159/000176410
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The prognostic value of maximal exercise testing soon after first myocardial infarction1985 · 16 citations
  2. 2Adverse Prognosis of ST Depression on the Resting Electrocardiogram in Stable Patients Following Acute Myocardial Infarction1996 · 4 citations
  3. 3Submaximal exercise testing early after myocardial infarction. Prognostic importance of exercise induced ST segment elevation.1984 · 33 citations
  4. 4Exercise‐provoked ST‐segment depression and prognosis in patients recovering from acute myocardial infarction. Significance and pitfalls1993 · 6 citations
  5. 5Prognostic significance of the ST-segment response during exercise test shortly after acute myocardial infarction. Comparison with other exercise variables1983 · 16 citations