Population
Patients undergoing percutaneous transluminal coronary angioplasty (PTCA)
Design
Review
Authors
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Systemic antiproliferative agents have not reduced restenosis; challenges this strategy and leaves open targeted delivery or alternative mechanisms.
The review highlights that despite understanding the role of smooth muscle cell proliferation in restenosis post-PTCA, systemic pharmacological interventions have failed to prevent it, suggesting a need for new delivery methods or deeper mechanistic understanding.
Lövqvist et al. (1993) studied this question.
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