Why the study?
To reliably detect immaturity, it is crucial to study cardiovascular organ function development, determine maturation-related changes in spontaneous short-term blood pressure variability and baroreflex sensitivity, and separate the effects of gestational versus postnatal age.
In premature infants, the maturation process is accompanied by increased baroreflex buffering of spontaneous short-term blood pressure oscillations, predominantly driven by gestational age.
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BRS maturation patterns may aid autonomic monitoring in preterms; leaves open predictive value or interventions pending prospective data.
Javorka et al. (2021) studied this question.
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