A new two-stage approach for nonlinear brain image registration is proposed. In the first stage, an active contour algorithm is used to establish a homothetic one-to-one map between a set of region boundaries in two images to be registered. This mapping is used in the second step: a two-dimensional transformation which is based on an elastic body deformation. This method is tested by registering magnetic resonance images to atlas images.
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Davatzikos et al. (1996) studied this question.
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