Key result
Acidic pH dilates muscle and skin vessels, whereas alkaline pH selectively constricts cutaneous beds.
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The responses of the vascular beds in skeletal muscle and skin to changes in blood pH on the acid and alkaline sides of the physiologic range were compared. Dilatation occurred in both cutaneous and muscular beds when the blood pH was shifted to the acid range. Dilatation also occurred in the muscle beds when the blood pH was shifted to the alkaline range but such change in blood pH caused vasoconstriction in skin.
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Déal et al. (1954) studied this question. Changes in blood pH (acidic and alkaline) vs. Physiologic pH range was evaluated on Vascular responses (dilatation or vasoconstriction) in skeletal muscle and skin. Shifts to acidic blood pH caused dilatation in both cutaneous and muscular beds, whereas alkaline pH caused dilatation in muscle but vasoconstriction in skin of pentobarbitalized dogs.
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