Why the study?
Both PET-derived myocardial flow reserve and MRI-measured right ventricular global longitudinal strain independently predict adverse cardiac events in CAD, but the prognostic value of evaluating both simultaneously using hybrid 13N-ammonia PET/MRI was unstudied.
Does simultaneous assessment of MFR and RVGLS by hybrid 13N-ammonia PET/MRI predict adverse cardiac events in patients with coronary artery disease?
Does simultaneous assessment of MFR and RVGLS by hybrid 13N-ammonia PET/MRI predict adverse cardiac events in patients with coronary artery disease?
Simultaneous assessment of MFR and RVGLS by hybrid 13N-ammonia PET/MRI provides independent prognostic value for predicting adverse cardiac events in patients with coronary artery disease.
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Hybrid PET/MRI MFR and RVGLS may refine CAD risk stratification; leaves open incremental value over standard models.
Myocardial flow reserve (MFR) derived from 13N-ammonia positron emission tomography (PET) is used to predict adverse cardiac events in patients with coronary artery disease (CAD). Right ventricular global longitudinal strain (RVGLS) measured by magnetic resonance imaging (MRI) is used to evaluate RV function and predict cardiac events. This study aimed to evaluate the prognostic value of MFR and RVGLS measured by hybrid 13N-ammonia PET/MRI in patients with CAD.
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Endo et al. (2022) studied this question.
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