Population
24 children (10 boys, 14 girls) with Laron syndrome
Design
Cohort
Follow-up
throughout infancy, childhood, and puberty
Authors
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Highlights need for sex-specific growth monitoring into adulthood in Laron syndrome; leaves open validation in larger cohorts.
Growth curves for Laron syndrome demonstrate severe postnatal growth retardation with no clear pubertal spurt, resulting in significantly reduced final adult heights.
Laron et al. (1993) studied this question.
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