Computational modeling demonstrates that the complex anisotropic fibre structure of the myocardium reduces deformation and stress during diastole and prevents long-axis rotation.
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Realistic fibre architecture may lower modeled diastolic stress; leaves open clinical validation and patient-specific modeling.
Stress and deformation results from finite element analyses are presented for a series of models of the human left ventricle. The myocardium has a complex anisotropic fibre structure, are made on both fibre orientation and on the ratio are made on both fibre orientation and on the ratio of the elastic moduli along and across the fibres. The results show that, at least in diastole, when the left ventricle is considered as a passive structure under the action of the internal blood pressure, the effect of the real fibre arrangement is generally to reduce deformation and also the direct stresses. In spite of fibre angle changing across the wall, the analyses correctly predict the lack of rotation of the left ventricle about the long axis.
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Yettram et al. (1983) studied this question.
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