Why the study?
Does the addition of radiotherapy to radical surgery improve outcomes in patients with primary non-metastatic retroperitoneal soft tissue sarcomas?
Does the addition of radiotherapy to radical surgery improve outcomes in patients with primary non-metastatic retroperitoneal soft tissue sarcomas?
The addition of radiotherapy to surgery for retroperitoneal sarcoma lacks level I evidence, though preoperative radiotherapy is preferred over postoperative due to lower toxicity risks.
Surgery is potentially curative for primary non-metastatic retroperitoneal soft tissue sarcomas (RPS), although patients remain at risk for local recurrence. To reduce this risk, the addition of radiotherapy to radical surgery may be considered. Nevertheless, level I evidence to support radiotherapy is currently lacking. The results from the EORTC-STBSG 62092-22092 studying this question are awaited. This manuscript addresses issues to consider when radiation-oncologists engage in a multidisciplinary treatment approach for RPS patients, including radiotherapy.
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Haas et al. (2017) studied this question.
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