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July 1, 1967The Journal of PhysiologyOpen Access

Electrophysiological study of the intestinal smooth muscle of the guinea‐pig

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Population

Guinea-pig intestinal smooth muscle (single cells of duodenum, jejunum, ileum, caecum, and rectum)

Design

Preclinical

Authors

HKHiroshi KuriyamaKagoshima UniversityTOTakuro OSAKyushu UniversityNTN. ToidaKyushu University

Discussion

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Implication

Baseline guinea-pig intestinal electrophysiology data; leaves open translation to human GI motility disorders.

Structured PICO

P
Population
Guinea-pig intestinal smooth muscle (single cells of duodenum, jejunum, ileum, caecum, and rectum)
I
Intervention
Electrophysiological measurements (including intracellular stimulation and extracellular polarizing method, with and without tetrodotoxin)
O
Outcome
Membrane properties (membrane potentials, spontaneous discharges, conduction velocities, chronaxies, effective membrane resistance, and time constant)surrogate

This preclinical study characterizes the baseline electrophysiological properties, including membrane potentials, conduction velocities, and chronaxies, across different regions of guinea-pig intestinal smooth muscle.

Cite This Study

Kuriyama et al. (1967) studied this question.

synapsesocial.com/papers/6a70831b5671bbf00bc2b8a6https://doi.org/10.1113/jphysiol.1967.sp008248
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Also Consider

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  1. 1Conduction in smooth muscle: comparative structural properties1960 · 135 citations
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  4. 4Effect of sodium deficiency of the action potential of the smooth muscle of ureter1964 · 28 citations
  5. 5Patterns of conduction in smooth muscle1963 · 43 citations