Entamoeba coli endotoxin was administered intravenously to cats and dogs.2. The changes in circulating levels of catecholamines and angiotensin following endotoxin were assayed by a continuous superfusion technique.3. The response of the dog was characterized by an immediate sustained rise in angiotensin levels and a later variable rise in catecholamine levels.4. The response of the cat was characterized by an early rise in catecholamine levels and a later rise in angiotensin levels.5. It is concluded that this species difference may reflect the relative importance of renin-angiotensin and sympatho-adrenal systems of dogs and cats, respectively.
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Hall et al. (1971) studied this question.
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