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October 27, 1989Science

Mutants of Pertussis Toxin Suitable for Vaccine Development

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Authors

MPMariagrazia PizzaImperial College LondonACAntonio CovacciNewron Pharmaceuticals (Italy)ABAntonella BartoloniUniversity of Siena

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Cite This Study

Pizza et al. (1989) studied this question.

synapsesocial.com/papers/6a708ae08031ec7bb1dc6a11https://doi.org/10.1126/science.2683073
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Human T cell clones define S1 subunit as the most immunogenic moiety of pertussis toxin and determine its epitope map.1989 · 61 citations
  2. 2Mortality and morbidity from invasive bacterial infections during a clinical trial of acellular pertussis vaccines in Sweden1988 · 67 citations
  3. 3Pertussis Toxin S1 Mutant with Reduced Enzyme Activity and a Conserved Protective Epitope1988 · 116 citations
  4. 4Promoter of the pertussis toxin operon and production of pertussis toxin1987 · 59 citations