Why the study?
Does pericardiocentesis with or without intrapericardial thiotepa improve symptoms and survival in patients with malignant pericardial effusion?
Population
7 patients with malignant pericardial effusion due to advanced cancer
Design
Case_series
Follow-up
Up to 59 months
Authors
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May offer rapid symptom relief in malignant pericardial effusion; leaves open survival benefit and adjunctive thiotepa role.
Does pericardiocentesis with or without intrapericardial thiotepa improve symptoms and survival in patients with malignant pericardial effusion?
Pericardiocentesis, potentially combined with intrapericardial thiotepa, provides immediate symptomatic relief and prevents reaccumulation in patients with malignant pericardial effusion, though overall prognosis remains dictated by the underlying malignancy.
Cozzi et al. (2010) studied this question.
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