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April 1, 1980CancerOpen Access

Cardiac tamponade as a presentation of extracardiac malignancy

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Why the study?

Does pericardiectomy improve survival compared to pericardiocentesis or medical therapy alone in patients with cardiac tamponade from extracardiac malignancy?

Population

Patients with extracardiac malignancy presenting with acute pericardial effusion and tamponade

Comparison

Pericardiectomy with or without ancillary radio… vs Pericardiocentesis or radio- or chemotherapy alone

Design

Case_series

Authors

RFRichard S. FraserChester ZooJVJ ViloriaMontreal General HospitalNWNai‐San WangUniversity Health Network

Discussion

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Implication

Pericardiectomy may be associated with longer survival in malignant tamponade; leaves open whether surgery should be preferred in prospective trials.

Structured PICO

Does pericardiectomy improve survival compared to pericardiocentesis or medical therapy alone in patients with cardiac tamponade from extracardiac malignancy?

P
Population
Patients with extracardiac malignancy presenting with acute pericardial effusion and tamponade (3 new cases, 26 cases from literature review)
I
Intervention
Pericardiectomy with or without ancillary radio- or chemotherapy
C
Comparator
Pericardiocentesis or radio- or chemotherapy alone
O
Outcome
Survivalhard clinical

Pericardiectomy may offer a survival advantage over pericardiocentesis alone in patients presenting with cardiac tamponade due to extracardiac malignancy.

Cite This Study

Fraser et al. (1980) studied this question.

synapsesocial.com/papers/6a708d1f87f921057127bf95https://doi.org/10.1002/1097-0142(19800401)45:7<1697::aid-cncr2820450730>3.0.co;2-j
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pleural pericardial window for palliation of cardiac tamponade due to cancer1970 · 47 citations
  2. 2The Management of Malignant Pericardial Effusions1973 · 62 citations
  3. 3Conservative management of malignant pericardial effusion1974 · 107 citations
  4. 4The Spread of Lung Cancer to the Heart, Pericardium and Great Vessels1974 · 30 citations