Why the study?
What are the long-term durability and reasons for reoperation in patients receiving fresh homografts for aortic valve replacement?
Population
655 patients who received fresh homografts for aortic valve replacement over a 23-year period. A subgroup of…
Design
Cohort
Follow-up
up to 23 years
Authors
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May inform durability counseling for fresh homografts; leaves open randomized comparisons with modern bioprostheses in younger patients.
What are the long-term durability and reasons for reoperation in patients receiving fresh homografts for aortic valve replacement?
Fresh homograft aortic valve replacement provides acceptable durability up to 23 years, with structural degeneration being the primary cause for reoperation, particularly in younger patients.
Janusz Sadowski (2003) studied this question.
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