May 26, 2003Archives of Internal Medicine
Aspirin and Clopidogrel in Acute Coronary Syndromes
Why the study?
Does adding clopidogrel to aspirin reduce cardiovascular events in patients with acute coronary syndromes without ST-segment elevation myocardial infarction?
Population
Patients having acute coronary syndromes without ST-segment elevation myocardial infarction, including those…
Comparison
Clopidogrel added to aspirin vs Aspirin alone
Design
Review
Authors
Discussion
Loading...
Member takes
Implication
May support dual antiplatelet therapy in NSTE-ACS; leaves open need for updated randomized confirmation.
Structured PICO
Does adding clopidogrel to aspirin reduce cardiovascular events in patients with acute coronary syndromes without ST-segment elevation myocardial infarction?
P
Population
Patients having acute coronary syndromes without ST-segment elevation myocardial infarction, including those with aspirin resistance
I
Intervention
Clopidogrel added to aspirin
C
Comparator
Aspirin alone
Combination therapy with aspirin and clopidogrel is beneficial for patients with acute coronary syndromes without ST-segment elevation myocardial infarction, particularly those with aspirin resistance.
Cite This Study
Jneid et al. (2003) studied this question.