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May 26, 2011Anesthesia & Analgesia

Cause and Effect or Conjecture? A Call for Consensus on Defining “Anesthesia-Related Mortality”

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Population

Children ≤18 years of age who received an anesthetic at a single tertiary pediatric hospital

Design

Editorial

Follow-up

30 days

Authors

JDJayant K. Deshpande

Discussion

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Overview

Anesthesia-related mortality remains rare but disproportionately affects children with pulmonary hypertension; leaves open the need for consensus definitions to refine risk stratification.

Structured PICO

P
Population
Children ≤18 years of age who received an anesthetic at a single tertiary pediatric hospital (n=56,263 children, 101,885 anesthetics)
I
Intervention
Anesthesia
O
Outcome
Anesthesia-related mortality (24-hour and 30-day)hard clinical

This editorial emphasizes the critical need for a standardized, validated consensus definition of anesthesia-related mortality to improve risk stratification and safety, especially for high-risk pediatric patients with cardiac disease.

Limitations

  • Focused only on mortality after anesthesia, excluding surrogate events like cardiac arrest
  • Insufficient number of anesthesia-related deaths (n=10) for meaningful statistical evaluation
  • Method for defining anesthesia-related death by expert panel is not validated for interrater reliability

Cite This Study

Jayant K. Deshpande (2011) studied this question.

synapsesocial.com/papers/6a70900331a3df824328d1a3https://doi.org/10.1213/ane.0b013e3182182199
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Postoperative Mortality in Children After 101,885 Anesthetics at a Tertiary Pediatric Hospital2011 · 242 citations
  2. 2A STUDY OF THE DEATHS ASSOCIATED WITH ANESTHESIA AND SURGERY1954 · 770 citations
  3. 3Perioperative cardiac arrest and its mortality in children. A 9‐year survey in a Brazilian tertiary teaching hospital2006 · 102 citations
  4. 4The Baltimore Anesthesia Study Committee1960 · 61 citations
  5. 5The Frequency of Anesthesia-Related Cardiac Arrests in Patients with Congenital Heart Disease Undergoing Cardiac Surgery2007 · 102 citations