Why the study?
Does levosimendan improve cardiac performance in patients undergoing cardiopulmonary bypass?
Population
18 patients undergoing cardiopulmonary bypass (CPB)
Comparison
Levosimendan administered 15 min before and… vs Placebo
Design
RCT, randomly assigned, placebo-controlled
Follow-up
6 hours after CPB
Authors
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May support levosimendan for post-CPB hemodynamic support; extends RCT evidence for inodilators in cardiac surgery.
Does levosimendan improve cardiac performance in patients undergoing cardiopulmonary bypass?
Levosimendan significantly improves cardiac output and reduces systemic vascular resistance after cardiopulmonary bypass without increasing perioperative arrhythmias.
Nijhawan et al. (1999) studied this question.
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