A Comparative Study of Blood Fibrinolytic Activity in Normal Women, Pregnant Women and Women on Oral Contraceptives

Summary A decrease in blood fibrinolytic activity in women taking chlormadinone compared with normal women was found (p<0.01). The mean fibrinolytic activity in pregnant women was significantly lower than that of normal women, those taking chlormadinone acetate and also those on a combined oestrogen‐progestagen preparation (p<0.001). No significant difference in fibrinolytic inhibitor content was observed when normal women were compared with pregnant women (p>0.2) and those taking chlormadinone (p>0.3). On the other hand, the women on a combined oestrogen‐progestagen preparation had a lower fibrinolytic inhibitor content than both normal women (p<0.001) and those receiving chlormadinone (p<0.02).