Why the study?
Does sympathetic inhibition with clonidine attenuate hypoxia-induced insulin resistance in healthy men?
Population
10 healthy men, mean age 23 ± 1 years, BMI 24.2 ± 0.8 kg/m².
Comparison
Hypoxia combined with sympathetic inhibition via… vs Normoxia, hypoxia alone, and normoxia with…
Design
RCT, in a random order
Follow-up
48 hours
Authors
Loading...
Clonidine attenuates hypoxia-induced insulin resistance; confirms sympathetic mediation and supports targeted trials in clinical hypoxia.
Does sympathetic inhibition with clonidine attenuate hypoxia-induced insulin resistance in healthy men?
Short-term sympathetic inhibition with clonidine attenuates hypoxia-induced insulin resistance in healthy men, suggesting a role for the sympathetic nervous system in this physiological response.
Peltonen et al. (2012) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: