Why the study?
Does prolonged exposure to hypobaric hypoxia increase sympathetic nerve activity in healthy humans?
Population
8 healthy volunteers, age 24 +/- 2 years
Comparison
Prolonged exposure to hypobaric hypoxia vs Sea level conditions (Copenhagen)
Design
Other
Follow-up
4 weeks
Authors
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May warrant BP monitoring during high-altitude exposure; leaves open mechanisms of sympathetic overactivity beyond chemoreflex activation.
Does prolonged exposure to hypobaric hypoxia increase sympathetic nerve activity in healthy humans?
Acclimatization to high altitude hypoxia is accompanied by a striking and long-lasting sympathetic overactivity that is not fully explained by chemoreflex activation or dehydration.
Hansen et al. (2003) studied this question.
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