Follow‐up tricuspid annular plane systolic excursion predicts survival in pulmonary arterial hypertension
Why the study?
Does achieving a follow-up TAPSE ≥ 2 cm predict improved survival in patients with pulmonary arterial hypertension?
Population
70 consecutive patients with pulmonary arterial hypertension who underwent baseline right heart…
Comparison
Follow-up tricuspid annular plane systolic… vs Follow-up TAPSE < 2 cm at one year
Design
Cohort
Follow-up
median 941 days (range, 3-2311 days)
Authors
Discussion
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Member takes
Implication
Follow-up TAPSE ≥2 cm may refine PAH prognosis; hypothesis-generating and requires validation before guiding serial monitoring.
Structured PICO
Does achieving a follow-up TAPSE ≥ 2 cm predict improved survival in patients with pulmonary arterial hypertension?
P
Population
70 consecutive patients with pulmonary arterial hypertension (PAH) who underwent baseline right heart catheterization and transthoracic echocardiogram, and survived to follow-up echocardiogram after initiation of PAH therapy.
I
Intervention
Follow-up tricuspid annular plane systolic excursion (TAPSE) ≥ 2 cm at one year
C
Comparator
Follow-up TAPSE < 2 cm at one year
O
Outcome
Survival (mortality) over a median follow-up of 941 dayshard clinical
Achieving a follow-up TAPSE ≥ 2 cm after initiation of PAH therapy is a strong predictor of survival and represents a potential treatment target.
Cite This Study
Mazurek et al. (2017) studied this question.