Why the study?
Does intravenous infusion of 10% fructose lead to direct assimilation by peripheral tissues in human subjects?
Does intravenous infusion of 10% fructose lead to direct assimilation by peripheral tissues in human subjects?
Intravenous fructose infusion demonstrates consistent arteriovenous differences, suggesting direct assimilation by peripheral tissues in humans.
Suggests possible direct peripheral fructose assimilation after IV infusion; hypothesis-generating and should not change practice without higher-level evidence.
Serial peripheral arteriovenous fructose differences were measured in 10 human subjects receiving a constant intravenous infusion of 10% fructose in water, following an initial priming injection. Maintenance of consistent and appreciable arteriovenous differences under these circumstances occurred in every case? and this finding is interpreted as evidence for direct assimilation of fructose by the peripheral tissues. 2. The problem of distinguishing between diffusion, assimilation and utilization is discussed.
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Itallie et al. (1953) studied this question.
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