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January 1, 1940Archives of Internal Medicine

Disseminated Lupus Erythematosus: A Cutaneous Manifestation of a Systemic Disease (Libman-Sacks)

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Authors

AGArthur M. GinzlerSaint Joseph Hospital

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Implication

Clinical review demonstrates that disseminated lupus erythematosus represents a widespread systemic disorder involving internal organs, highlighting that visceral damage occurs beyond skin lesions.

Key Points

  • To characterize disseminated lupus erythematosus as an underlying systemic disease associated with characteristic visceral organ damage rather than purely a skin condition.
  • Synthesized historical and dermatologic literature spanning seventy years regarding localized and generalized lupus erythematosus.
  • Evaluated clinical and anatomical evidence of visceral lesions and cutaneous manifestations described across systemic cases.
  • Disseminated lupus erythematosus constitutes a widespread systemic disease accompanied by characteristic clinical and anatomical visceral damage.
  • Systemic and visceral involvement can occur in patients even in the complete absence of cutaneous eruptions.

Cite This Study

Arthur M. Ginzler (1940) studied this question.

synapsesocial.com/papers/6a709bc1febe604dd7096016https://doi.org/10.1001/archinte.1940.00190070036003
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1THE SO-CALLED LIBMAN-SACKS SYNDROME1936 · 27 citations
  2. 2CHARACTERIZATION OF VARIOUS FORMS OF ENDOCARDITIS1923 · 108 citations
  3. 3FATAL CASE OF LUPUS ERYTHEMATOSUS, WITH POST-MORTEM.1925 · 5 citations
  4. 4LUPUS ERYTHEMATOSUS1938 · 15 citations
  5. 5NONBACTERIAL THROMBOTIC ENDOCARDITIS1936 · 49 citations