What question did this study set out to answer?

To evaluate the comparability and reproducibility of transepidermal water loss measurements using four commercial evaporimeters and determine optimal recording procedures.

April 1, 1989Contact Dermatitis

Comparability and reproducibility of the results of water loss measurements: a study of 4 evaporimeters

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Authors

JPJaliya PinnagodaWitten/Herdecke University RTRon A. TupkerSt. Antonius Ziekenhuis PCPieter Jan CoenraadsUniversity Medical Center Groningen

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Implication

Experimental study observes high measurement reproducibility but inter-probe variation across evaporimeters, highlighting the need for dynamic water-loss calibration.

Key Points

To evaluate the comparability and reproducibility of transepidermal water loss measurements using four commercial evaporimeters and determine optimal recording procedures.
Tested five probes across four ServoMed Evaporimeters (three single-probe, one double-probe) using a custom constant-rate in vitro evaporation device and in vivo testing on the volar forearm of one subject.
Evaluated probe stabilization dynamics over time to identify the optimum interval for recording transepidermal water loss.
Reproducibility of successive measurements was consistently high for all probes, but baseline values varied across four probes and one probe yielded values distinctly out of range.
Probe readings reached stabilization between 30 and 45 seconds post-application, supporting a standardized protocol of recording for 30 seconds after an initial 45-second stabilization window.
Standard manufacturer calibrations adjusting only for specified humidities and zero water loss proved insufficient, demonstrating the necessity of calibration against a constant water-loss source.

Cite This Study

Pinnagoda et al. (1989) studied this question.

synapsesocial.com/papers/6a709bc25671bbf00bc2bc57 https://doi.org/10.1111/j.1600-0536.1989.tb03139.x

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Implication

Experimental study observes high measurement reproducibility but inter-probe variation across evaporimeters, highlighting the need for dynamic water-loss calibration.

Comparability and reproducibility of the results of water loss measurements: a study of 4 evaporimeters

Discussion

Member takes

Implication

Key Points

Cite This Study

Comparability and reproducibility of the results of water loss measurements: a study of 4 evaporimeters

Discussion

Member takes

Implication

Key Points

Cite This Study

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