Why the study?
Does antidepressant treatment with selective serotonin reuptake inhibitors improve cardiovascular outcomes in patients with cardiovascular disease and depression?
Population
Patients with cardiovascular disease and major depressive disorder
Design
Review
Authors
Discussion
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Member takes
Implication
Depression warrants routine screening in CHD and HF outpatients; leaves open whether SSRIs improve cardiovascular outcomes.
Structured PICO
Does antidepressant treatment with selective serotonin reuptake inhibitors improve cardiovascular outcomes in patients with cardiovascular disease and depression?
P
Population
Patients with cardiovascular disease (including coronary heart disease and congestive heart failure) and major depressive disorder
I
Intervention
Antidepressant treatment with selective serotonin reuptake inhibitors (SSRIs)
Major depression is highly prevalent but under-recognized in cardiovascular disease, and while SSRIs are safe and improve quality of life, their impact on cardiovascular outcomes remains uncertain.
Cite This Study
Mary A. Whooley (2006) studied this question.